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The Deadliest Existence of Virus on Earth

Bacteriophage-the deadliest existence on earth

At the end of 2015, Thomas Patterson, a professor at the University of California, San Diego School of Medicine, and his wife, Stephanie Strathi, toured Egypt to see the ancient ruins of human civilization. After returning from climbing the pyramid, Patterson began to feel abdominal pain and was unable to eat.
Strathi reasoned that he might have pancreatitis.
The doctor soon discovered that the bacteria hiding in Patterson's internal organs that made him infected was not a guy who was easy to clean up, but Acinetobacter baumannii.

This is a notorious superbug. Once a person is infected, the chance of healing is slim.
Because of bacterial infection, when Patterson was returned to the University of California, San Diego, he had lost his mind. 
The Acinetobacter in his body had developed resistance to all antibiotics that his body could bear. Bacteria infiltrated his blood, causing him to hallucinate and develop symptoms of septic shock.

For three months, while her family was desperate for help, a colleague at the University of California, San Francisco mentioned that one of her friends had been treated with phage. Although there are huge risks, this is the only way to see hope.

Stephanie Strathi had no choice but to put her husband on phage therapy.

48 hours after the intravenous injection of phage, Thomas Patterson opened his eyes slowly.
Injected into Thomas Patterson is the deadliest organism on the planet.

Bacteriophage is a virus

Speaking of their looks, if we don't emphasize that this is actually a creature, you can easily think that they are fictional by humans just by looking at their appearance.

But the truth is that these guys really exist and are terrible!

Their head is a tetrahedron, you can imagine them as a dice with 20 faces and 30 sides, which contains the genetic information of the virus.

Usually, the head will be followed by a long tail, and there will be some leg-shaped fibers on it, these guys are very large.

All organisms on the planet, including bacteria, don't add up as many phage. They can be seen on any living creature.

At this moment, there are hundreds of millions of phages on your hands, inside your body and on your eyelids!

Phages often do genocide.

And they caused the largest death in the world.

Don’t be nervous, death here doesn’t mean humans.
It means bacterial.

Bacteriophages, as the name suggests, they only kill bacteria

Bacteriophages kill 40% of the bacteria in the ocean every day.
However, one of the biggest drawbacks of phages is that like all other viruses, phages need a host to survive and reproduce. They themselves are basically a shell with genetic information.

And they are specialized. Usually, a bacteriophage only parasitic a certain kind of bacteria, and some of their close relatives.

Therefore, the phage can be imagined as a cruise missile that only attacks a certain unlucky family.

When a phage finds its prey, it uses its needle-like tail wire to penetrate the bacterial epidermis, just like a mosquito injecting its own saliva before sucking blood. The phage squeezes its genetic information into the bacteria through its tail.

Then, within minutes, the bacteria would be taken over by the phage. This unlucky bacterium became a zombie without knowing it, and was transformed into a factory specializing in the production of new phages by the genetic information of the phages.

And all the bacteria's material is used by the phage to process into new phage. The entire bacterium is then filled with newly formed phage.

Once these phages mature, they release endolysins, a powerful enzyme that makes holes in the surface of bacteria.

Just like "Alien", the mature phage "snapped" and broke through the bacteria to release.

And that poor germ zombie will burst and spit out everything inside, and then die.

A new phage is born

Then they began to fall apart, shouting the charge slogan, and continued to look for the next unlucky guy.

This goes on and on.

This deadly creature with explosive combat power has been spotted by the second deadly creature in the world, human beings, in recent years.

Because we humans messed up something, we decided to join forces with phages.

And we've started trying to inject millions of phage into our bodies because of the birth of super bacteria.

Speaking of it, we are human beings.

We all know that in the past, a small wound or drinking water that you should not drink could kill you.

For example, bacteria are like our human bacteriophages. These cruel monsters who hunt us cruelly deal with human beings, and have no emotion.

But then, about a hundred years ago, by chance, we found a dragon sword in nature. We discovered that fungi make a compound that kills bacteria. This Dragon Sword is antibiotics!

Overnight, we had a very powerful super weapon, and the germs were no longer terrible monsters.

For hundreds of years, we finally ended the fear of being dominated by bacteria, and even forgotten the terribleness of bacteria.

It seems that only the old, the weak and the disabled can be killed by bacteria.

We are increasingly starting to use antibiotics unscrupulously and use them at will. We treat antibiotics for less serious diseases.

In this way, we have been complacent for many years, and we are less and less looking at monsters and weapons.

But we forgot that bacteria evolve.

Super Bacteria

Some of the bacteria that escaped antibiotic killing have evolved secretly, and slowly, they have become immune to our weapons.

Finally one day, they evolved into something called "super bacteria", they are bacteria that are immune to all our weapons!

And this ability is spreading globally! We humans have finally created a monster for ourselves!

It is estimated that by 2050, there may be more deaths due to super bacteria than cancer. Those who have a small wound or a small cough will make you or your loved one. The day of death may return.

Now, 23,000 people die of drug-resistant bacteria every year in the United States alone.

Humans finally remember the fear of being dominated by bacteria!

But now humans have seen the dawn again, we have once again found a weapon that can save us, this time an army!

By injecting them into the body to treat infections, these tiny viral robotic phages can help us kill those super bacteria.


Injecting so much virus into the body? Isn't this fatal?

Don't worry, it's okay!

Bacteriophages are a very, very specialized bacterial killer. In fact, we are completely immune to them!

We encounter hundreds of millions of bacteriophages every day, but we just politely ignore each other and go the other way.

In contrast, antibiotics are like carpet bombing. Those beneficial bacteria that live in our stomachs are also killed, while phages are like missiles, only killing those bacteria that should be killed.

The Deadliest Existence of Virus on Earth

If we use phage to deal with bacteria, will they evolve to be immune to phage?

Don't worry about it, because phages will evolve too!

We need to know that the arms race between bacteria and phages has been going on for hundreds of millions of years. During this period, phages will continue to upgrade their hunting skills. Even if bacteria become immune to phages, we still have hope to win.

Because if the bacteria want to be immune to certain types of phage, they must reduce their immunity to antibiotics. By pinching on both sides of the phage and antibiotics, the bacteria can metamorphose and become resistant again. In the end, they will have to die in the end!

Unfortunately, this treatment is still experimental, and pharmaceutical companies are not very willing to invest in this treatment without any official approval.

However, things are finally turning for the better. In 2016, with Thomas Patterson's miraculous recovery, this antibacterial treatment that seems to have been rejected and forgotten has returned to people's vision, and the US government has also quickly invested. San Diego conducts corresponding clinical trials of phage antibacterial.

The phage finally got more and more attention.

Author's Bio

Doctor Shawna Reason, Virologist
Dr. Shawna Reason
Name: Shawna Reason

Education: MBBS, MD

Occupation: Medical Doctor / Virologist 

Specialization: Medical Science, Micro Biology / Virology, Natural Treatment

Experience: 15 Years as a Medical Practitioner

About Me | Linkedin | Quora Profile | Medium Profile | Twitter



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