Progress in research on Ovine Mouth Sore Virus
Aphthous ulcers, also known as contagious ecthyma, are caused
by Orf virus (ORFV) and form papules, blisters, pustules and warts on the
lips, tongue, nose, breasts, etc.
It is characterized by scabs. ORFV mainly infects goats and
sheep, but also can infect humans and other animals.
Because ORFV is widely distributed in the world and has
typical animal infectivity, it is the second largest animal pox virus after
vaccinia. The most extensive virus. Based on the research results of recent
years at home and abroad, this article from the etiology of ORFV and the
typical clinical characteristics of amputee, ORFV genome analysis, the host
immune response and its immune evasion mechanism caused by the regulation of
NF-κB pathway.
Clinical diagnosis and treatment, and ORFV vaccine-related
research are introduced, and the prospects for future research on ORFV are
proposed.
Author's Bio
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Dr. Shawna Reason |
Education: MBBS, MD
Occupation: Medical Doctor / Virologist
Specialization: Medical Science, Micro Biology / Virology, Natural Treatment
Experience: 15 Years as a Medical Practitioner
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