Types and Category of Alpha virus
Definition of Alpha Virus: Alpha virus, a genus of the Toga virus family. Spherical viruses with a diameter of 50-70 nm.
Medical Name: Alpha virus
English Name: Alphavirus
The diameter is: 50-70nm
Molecular weight: 30000
Meaning of Alphavirus
The encapsulated icosahedral nucleocapsid is 30-40 nanometers in the envelope. The specific gravity is 1.18-1.25. There are two types of structural proteins (capsid protein: molecular weight 30,000; envelope protein: molecular weight 52,000). It can infect humans, often causing children with hemorrhagic fever syndrome, arthralgia, fever and other symptoms.
What types of Viruses are Affiliated to Alpha Virus?
- Sin-dbis virus
- Chikungunya virus
- Eastern equine encephali-tis virus
- Western equineencephalitis virus
- Mayaru Virus (Mayarovirus)
- Semliki forest virus (Semliki forest virus)
- Venezuelan equine encephalitis virus (Venezuelan equine encephalitisvirus)
Coxsackie virus Coxsackie virus is a nucleovirus (Picornavirus). Virus particles are icosahedrons with a diameter of 27-28 nanometers.
The particles contain RNA (impregnating nucleic acid) with a molecular weight of 2.0 X 106.
In 1948 by G. Dalldorf and G. M. Sickles was isolated from the feces of polio-like paralysis patients in Coxsackie, New York, USA. It shows strong pathogenicity to mole rats.
What are the categories of Alpha viruses?
According to pathological studies, it can be roughly divided into two categories, A and B.
There are 23 species in category A and 6 species in category B. It is an oral infection to people, causing aseptic meningitis, herpes angina, epidemic myalgia, hand-foot-mouth disease and so on.
Type B can fully proliferate in simian kidneys, human amniotic membrane, HeLa cells, FL and other strains of cells, showing cell degeneration, but type A does not show obvious cell degeneration except for a part.
Like polio virus and ECHO virus, guanidine can inhibit proliferation. Interference can be found between Type B and poliovirus, both in vitro and in vivo.
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Dr. Shawna Reason |
Education: MBBS, MD
Occupation: Medical Doctor / Virologist
Specialization: Medical Science, Micro Biology / Virology, Natural Treatment
Experience: 15 Years as a Medical Practitioner
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