Scientists discover new results of human genome sequencing, which is expected to promote research on human diseases Introduction: Recently, researchers at the University of Maryland School of Medicine discovered a new result of human genome sequencing. This progress is expected to promote future research aimed at understanding the impact of human genome variations on human diseases.   Is gene sequencing the only method of genetic testing? Gene sequencing is only one of the methods of genetic testing. It is also called gene profile sequencing, which is an internationally recognized standard for genetic testing.   Recently, researchers from the University of Maryland School of Medicine (UMSOM) published a paper entitled "Haplotype-resolved diverse human genomes and integrated analysis of structural variation" in the journal Science, announcing a new achievement in human genome sequencing.   The researchers detailed the sequencing of 64 complete human genomes. Th

The Longevity Gene FOXO3 protects neural stem cells in the brain from stress mechanisms In a new study, researchers from the Weill Cornell Medical College in the United States have discovered that a gene FOXO3 related to the long lifespan of humans can protect neural stem/progenitor cells (NSPC) in the brain. Free from the harmful effects of stress. Related research results were recently published in the journal Nature Communications, with the title of the paper "Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification".     Do centenarians have unusual version of the FOXO3 gene? Research on people who live over 100 years old shows that many people have an unusual version of the FOXO3 gene.  This discovery prompted Dr. Jihye Paik, associate professor of pathology and laboratory medicine at Weill Cornell Medical College, and her colleagues to study how this gene promotes brain health during aging.   In 201

  Whole Genome Sequencing of Artificial Allopolyploid of Muskmelon Reveals the Important Evolution of Allopolyploid Genome The team of Professor Jinfeng Chen from Nanjing Agricultural University and collaborators completed the chromosome-level genome assembly of artificially synthesized polyploidy for the first time through whole-genome sequencing.  In the comparative analysis at the whole-genome level, it was detected that there were sub-genes in the early genome evolution of allotetraploid in Melon Genome dominance, found that heterologous doubling leads to phenotypic dominance and initially revealed its regulatory mechanism. Cucumber Crop    Cucumber (CucumissativusL.) (2n=2x=14) is an important vegetable crop in the world. It has experienced an evolutionary bottleneck in the process of domestication, so its genetic basis is particularly narrow.  Professor Chen Jinfeng made an interspecific hybridization between cultivated cucumbers and wild pickled cucumbers (C. hystrixChakr.,

We always see that Americans are allergic to peanuts, but Chinese do not. Are peanuts still picking people? Why do we always see reports of peanut allergies in Americans, but not reports of allergies in Chinese people? Why do we always see reports of peanut allergies in Americans, but not reports of allergies in Chinese people? Let us start with the summary: Because Chinese people eat peanuts less frequently and geographically than foreign countries, and the content of allergens in peanuts produced in China is less than that in foreign countries, the proportion of peanut allergies in China is relatively small. But the absolute number is not necessarily small.   1. Hygiene Hypothesis for Peanut Allergies On the issue of differences between China and the United States. In 1989, Strachan first proposed the hygiene hypothesis in a landmark article to explain the inverse relationship between family size and/or hygiene and susceptibility to allergic diseases.  The subjects of t

  Re-connection in the Animal Kingdom This is how the strongest alliance organization in history was born, gathering superheroes from all sides to show off their power, saving the world in dire straits, and resisting the invasion of dark forces. This is the "Avengers". Compared with the superheroes of the "Avengers", the animal kingdom also has a "reunion". Now please collect this movie guide from the Animal Avengers.   A sudden evil force poses a deadly threat to the earth, and no superhero can resist it alone. This is how the strongest alliance organization in history was born, gathering superheroes from all sides to show off their power, saving the world in dire straits, and resisting the invasion of dark forces.  This is the "Avengers". Compared with the superheroes of the "Avengers", the animal kingdom also has a "reunion". Now please collect this movie guide from the Animal Avengers.   It is no exaggeration to ca